Selected Publications

MacKinnon RN, Wall M, Zordan A, Nutalapati S, Mercer B, Peverall J and Campbell LJ 2013. Genome organisation and the role of centromeres in evolution of the erythroleukaemia cell line HEL. Evol Med Publ Health 2013:225-240

MacKinnon RN and Campbell LJ 2013. Chromothripsis under the microscope: A cytogenetic perspective of two cases of AML with catastrophic chromosome rearrangement. Cancer Genet 236:208-251

Ta L, Zordan A, Mercer B, Campbell LJ and MacKinnon RN 2013. The breakage-fusion-bridge cycle producing MLL amplification in a case of myelodysplastic syndrome. J Cancer Res 2013 Article ID 452809 Open access

MacKinnon RN, Selan C, Zordan A, Wall M, Nandurkar H and Campbell LJ 2012. CGH and SNP array using DNA extracted from fixed cytogenetic preparations and long-term refrigerated bone marrow specimens. Mol Cytogenet 5:10 Open access

Chin L-K, Chea CY, Michael PM, MacKinnon RN and Campbell LJ 2012. 11q23 Rearrangement and Duplication of the MLLT1-MLL Gene Fusion in Therapy-Related Acute Myeloid Leukemia. Leukemia Lymphoma 53:2066-8

Wall M, Rayeroux KR, MacKinnon RN, Zordan A and Campbell LJ 2012. ETV6 deletion is a common additional abnormality in patients with myelodysplastic syndromes/acute myeloid leukemia and monosomy 7. Haematologica 97:1933-6 Open access

MacKinnon RN and Campbell, LJ. 2011. The role of dicentric chromosome formation and secondary centromere deletion in the evolution of myeloid malignancy. Genetics Research International Article ID 643628. Open access

MacKinnon RN, Kannourakis G, Wall M, and Campbell LJ 2011. A cryptic deletion of 5q provides further evidence for a minimally deleted region in myelodysplastic syndromes. Cancer Genet 204:187-94.

MacKinnon RN, Duivenvoorden HM and Campbell LJ. 2011. Unbalanced translocation of 20q in AML and MDS often involves interstitial rather than terminal deletion of 20q. Cancer Genet 204:153-61.

MacKinnon RN, Selan C, Wall M, Baker E, Nandurkar H and Campbell LJ 2010. The Paradox of 20q11.21 Amplification in a Subset of Cases of Myeloid Malignancy with Chromosome 20 Deletion. Genes Chr Cancer 49:998–1013

MacKinnon RN and Campbell LJ 2007. Dicentric chromosomes and 20q11.2 amplification in MDS/AML with apparent monosomy 20. Cytogenet Genome Res 119:211-220.

MacKinnon RN and Chudoba I. 2010.  Invited book chapter. M-FISH and M-BAND. In: Campbell LJ. Editor, Cancer Cytogenetics: Methods and Protocols. Humana Press Methods Mol Biol 730:203-18.

MacKinnon RN and Campbell LJ. 2010. Invited book chapter. Monosomy 20 in the karyotypes of myeloid malignancies is usually the result of misclassification of unbalanced chromosome 20 abnormalities. In: Urbano, K.V. Ed, Advances in Genetic Research Volume 2 pp 57-72. Nova Science Publishers. Open Access

Shaffer LG, Slovak ML, Campbell LJ (eds). ISCN (2009): An International System for Human Cytogenetic Nomenclature. S. Karger, Basel 2009.

MacKinnon RN, Patsouris C, Chudoba I and Campbell LJ 2007. A FISH comparison of variant derivatives of the recurrent dic(17;20) of myelodysplastic syndromes and acute myeloid leukemia: Obligatory retention of genes on 17p and 20q may explain the formation of dicentric chromosomes. Genes Chromosomes Cancer 46:27-36.

MacKinnon RN and Campbell LJ December 2005.  A comparison of two contrasting recurrent isochromosomes 20 found in myelodysplastic syndromes suggests that retention of proximal 20q is a significant factor in myeloid malignancies.  Cancer Genet Cytogenet. 163:176-179.

Patsouris C, Michael PM, Campbell LJ 2002 A new nonrandom unbalanced t(17;20) in myeloid malignancies. Cancer Genet. Cytogenet. 138:32-7.

Reid AG, Swanton S, Grace C, Campbell LJ, Green AR, Nacheva EP; United Kingdom Cancer Cytogenetics Group (UKCCG) 1993. Double Philadelphia masquerading as chromosome 20q deletion – a new recurrent abnormality in chronic myeloid leukaemia blast crisis. Br. J. Haematol. 123:442-8.

Bench AJ, Nacheva EP, Hood TL, Holden JL, French L, Swanton S, Champion KM, Li J, Whittaker P, Stavrides G, Hunt AR, Huntly BJ, Campbell LJ, Bentley DR, Deloukas P, Green AR 2000. Chromosome 20 deletions in myeloid malignancies: reduction of the common deleted region, generation of a PAC/BAC contig and identification of candidate genes. UK Cancer Cytogenetics Group (UKCCG). Oncogene 2000 19(:3902-13.

Campbell LJ, Garson OM 1994. The prognostic significance of deletion of the long arm of chromosome 20 in myeloid disorders. Leukemia. 8:67-71.